Lyell Immunopharma, Inc. is a late-stage clinical company advancing a pipeline of next-generation chimeric antigen receptor (CAR) T-cell therapies for patients with hematologic malignancies and solid tumors. The Company’s product candidates include LYL314 and LYL273. Its LYL314, which is in Phase I/II clinical development, is a dual-targeting CD19/CD20 CAR T-cell product candidate designed to increase complete response rates and prolong the duration of response as compared to the approved CD19-targeted CAR T-cell therapies and is under evaluation trial for the treatment of patients with relapsed and/or refractory large B-cell lymphoma. The Company has acquired the global rights to LYL273 (formerly GCC19CART), a novel autologous guanylyl cyclase-C (GCC)-targeted CAR T-cell product candidate for the treatment of metastatic colorectal cancer (mCRC) and other GCC-expressing cancers.
Company Information
About this company
Key people
Lynn Seely
President, Chief Executive Officer, Interim Principal Financial Officer, Director
Stephen Hill
Chief Operating Officer
Gary Lee
Chief Scientific Officer
Richard D. Klausner
Chairman of the Board
Catherine Friedman
Lead Independent Director
Mark Bachleda
Director
Otis W. Brawley
Independent Director
Elizabeth G. Nabel
Independent Director
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Key facts
- Shares in issue21.24m
- EPICLYEL
- ISINUS55083R2031
- LocationUnited States
- SectorHealthcare
- IndustryBiotechnology & Drugs
- Market cap$513.68m
- Employees300
- ExchangeNASDAQ
- Index
- Website
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