MAIA Biotechnology Inc (MAIA) USD0.0001
$0.02
(0.98%)
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$0.02
(0.98%)
Deal for just £11.95 per trade in a
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Lifetime ISA
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SIPP
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Fund and Share Account
Business summary
MAIA Biotechnology, Inc. is a clinical-stage biopharmaceutical company developing targeted immunotherapies for cancer. The Company's THIO (6-thio-dG, 6-thio-2'-deoxyguanosine) is a first-in-class investigational telomere-targeting agent in clinical development to evaluate its activity in Non-Small Cell Lung Cancer (NSCLC). The modified nucleotide 6-thio-2-deoxyguanosine (THIO) induces telomerase-dependent telomeric DNA modification, DNA damage responses, and selective cancer cell death. THIO-damaged telomeric fragments accumulate in cytosolic micronuclei and activates both innate (cGAS/STING) and adaptive (T-cell) immune responses. The sequential treatment with THIO followed by PD-(L)1 inhibitors resulted in tumor regression in advanced, in vivo cancer models by induction of cancer type-specific immune memory. THIO is being developed as a second or later line of treatment for NSCLC for patients that have progressed beyond the standard-of-care regimen of existing checkpoint inhibitors.
Contact details
Important dates
General stock information
- Short code:
- MAIA
- ISIN:
- US5526411021
- Market cap:
- $49.14 million
- Shares in issue:
- 25.33 million
- Sector:
- Biotechnology
- Exchange:
- -
- Country:
- United States
- Currency:
- US dollar
- Indices:
- n/a
Key personnel
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